LymphedemaV1, Main, Exploration, bibRecord, 007D73

Risk of decline in upper-body function and symptoms among older breast cancer patients

Identifieur interne : 007D73 ( Main/Exploration ); précédent : 007D72; suivant : 007D74

Risk of decline in upper-body function and symptoms among older breast cancer patients

Auteurs : Jennifer L. Westrup [États-Unis] ; Timothy L. Lash [États-Unis] ; Soe Soe Thwin [États-Unis] ; Rebecca A. Silliman [États-Unis]

Source :

Journal of general internal medicine [ 0884-8734 ] ; 2006.

RBID : Pascal:06-0373679

Descripteurs français

Pascal (Inist)
- Tumeur maligne, Facteur risque, Lymphoedème, Epidémiologie, Symptomatologie, Personne âgée, Age, Glande mammaire, Malade, Complication, Traitement, Médecine, Cancer sein, Tumeur sein.
Wicri :
- topic : Personne âgée, Médecine.

English descriptors

KwdEn :
- Age, Breast cancer, Breast tumor, Complication, Elderly, Epidemiology, Lymphedema, Malignant tumor, Mammary gland, Medicine, Patient, Risk factor, Symptomatology, Treatment.

Abstract

BACKGROUND: Decline In upper-body function and development of upper-body symptoms are adverse effects of breast cancer therapy and may affect functional independence, particularly among older survivors. The long-term risks and predictors are poorly understood. OBJECTIVE: To characterize the risk of decline in upper-body function and development of symptoms over 4 years of follow-up. DESIGN; We used a prospective cohort design. PARTICIPANTS: Six hundred and forty-four early stage breast cancer patients 65 years old or older at surgery enrolled In Rhode Island, North Carolina, Minnesota, and Los Angeles between 1996 and 1999. MEASUREMENTS: Upper-body function and symptoms were self-reported at baseline, 6, 15 months, and annually thereafter to 51 months' after surgery. RESULTS: One half of the participants had a decline in upper-body function and one-quarter developed upper-body symptoms. Breast cancer patients were 5-fold more likely to have a decline in upper-body function over 4 years of follow-up than a similar cohort without breast cancer. Better baseline mental health protected against a decline in upper-body function (odds ratio [OR]=0.93, 95% confidence interval [CI] 0.88 to 0.97 for 8-point higher mental health index). Baseline obesity (OR for body mass index [BMI] ≥ 30 kg/m² vs <30 kg/m²=2.5, CI=1.6 to 4.0) and axillary node dissection (OR for axillary dissection vs not =3.9, CI=1.1 to 14) predicted the development of upper-body symptoms. CONCLUSIONS: Primary care physicians should address upper-body function and symptoms with older breast cancer patients, and Inform them that these complications of breast cancer treatment are common.

Url:

http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1484738

Affiliations:

Le document en format XML

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<profileDesc><textClass><keywords scheme="KwdEn" xml:lang="en"><term>Age</term>
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<term>Epidemiology</term>
<term>Lymphedema</term>
<term>Malignant tumor</term>
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<term>Patient</term>
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<keywords scheme="Pascal" xml:lang="fr"><term>Tumeur maligne</term>
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<term>Epidémiologie</term>
<term>Symptomatologie</term>
<term>Personne âgée</term>
<term>Age</term>
<term>Glande mammaire</term>
<term>Malade</term>
<term>Complication</term>
<term>Traitement</term>
<term>Médecine</term>
<term>Cancer sein</term>
<term>Tumeur sein</term>
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<front><div type="abstract" xml:lang="en">BACKGROUND: Decline In upper-body function and development of upper-body symptoms are adverse effects of breast cancer therapy and may affect functional independence, particularly among older survivors. The long-term risks and predictors are poorly understood. OBJECTIVE: To characterize the risk of decline in upper-body function and development of symptoms over 4 years of follow-up. DESIGN; We used a prospective cohort design. PARTICIPANTS: Six hundred and forty-four early stage breast cancer patients 65 years old or older at surgery enrolled In Rhode Island, North Carolina, Minnesota, and Los Angeles between 1996 and 1999. MEASUREMENTS: Upper-body function and symptoms were self-reported at baseline, 6, 15 months, and annually thereafter to 51 months' after surgery. RESULTS: One half of the participants had a decline in upper-body function and one-quarter developed upper-body symptoms. Breast cancer patients were 5-fold more likely to have a decline in upper-body function over 4 years of follow-up than a similar cohort without breast cancer. Better baseline mental health protected against a decline in upper-body function (odds ratio [OR]=0.93, 95% confidence interval [CI] 0.88 to 0.97 for 8-point higher mental health index). Baseline obesity (OR for body mass index [BMI] ≥ 30 kg/m<sup>2</sup>
 vs <30 kg/m<sup>2</sup>
=2.5, CI=1.6 to 4.0) and axillary node dissection (OR for axillary dissection vs not =3.9, CI=1.1 to 14) predicted the development of upper-body symptoms. CONCLUSIONS: Primary care physicians should address upper-body function and symptoms with older breast cancer patients, and Inform them that these complications of breast cancer treatment are common.</div>
</front>
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<name sortKey="Lash, Timothy L" sort="Lash, Timothy L" uniqKey="Lash T" first="Timothy L." last="Lash">Timothy L. Lash</name>
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Risk of decline in upper-body function and symptoms among older breast cancer patients

Risk of decline in upper-body function and symptoms among older breast cancer patients

Source :

Descripteurs français

English descriptors

Abstract

Links toward previous steps (curation, corpus...)

Le document en format XML

Pour manipuler ce document sous Unix (Dilib)

Pour mettre un lien sur cette page dans le réseau Wicri

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